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also known as TNFRSF17) in plasma cell malignancies)

Blood 119, 36293637

37 Furthermore, even if CRF application protects against gastric ulcers, 38 exogenous administration of CRF can reproduce cardinal features of diarrhea predominant irritable bowel syndrome including anxiogenic behavior, enhanced visceral pain to colorectal distention, increased colonic mucus secretion, propulsive motility, development of watery stool/diarrhea, and increased colonic mucosal permeability facilitating bacterial translocation into colonic tissue

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[DOI] [PubMed] [Google Scholar] 148.Raymond M., Li P., Mangin J.-M., Huntsman M., Gallo V

A phase I/II study of prexasertib in combination with irinotecan in patients with relapsed/refractory desmoplastic small round cell tumor and rhabdomyosarcoma [abstract]