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Loss of pqm-1 in a daf-2(e1370) mutant increased the fat-7p::fat-7::gfp reporter activity (Supplementary Fig

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The peptide activates melanocortin-1 receptors and upregulates tyrosinase enzyme production, but tyrosinase needs UV-induced oxidative stress to catalyze the chemical reactions that polymerize melanin

Curcumin has considerable clinical potential in other chronic diseases such as cardiovascular and metabolic diseases or cancer [114,115,116]