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Description
Chronic exposure to toxins increases the demand on detoxification systems
doi: 10.1007/S11882-012-0296-X 203 Briceno NoriegaDZenkerHECroesCAEwazARuinemans-KoertsJSavelkoulHFJet al
300 , R428436 (2011)
Drug-metabolizing enzymes chemically modify a variety of substituents on drug molecules, thereby either rendering the drugs inactive or facilitating their elimination by increasing solubility and ultimately excretion in the urine or bile
Oncotarget 7 (31), 5052250534
This concept attracted significant interest from obesity researchers and pharmaceutical development teams
