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Several animal studies using mouse models explain that TMAO is involved in platelet reactivity through the TF pathway, which contributes to major adverse cardiovascular events (MACE)
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Effects of Oral L-Carnitine Administration in Narcolepsy Patients: A Randomized, Double-Blind, Cross-Over and Placebo-Controlled Trial
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In addition, a non-enzymatic product of the prostaglandin D2 synthase gene ( PGD2S ), whose expression is upregulated by acetylcarnitine treatment with 100 mg/kg body weight [134], has been shown to have anti-inflammatory properties that may help protect the brain from ischemiareperfusion injury [72]
