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Transforming growth factor-1 upregulates keratan sulfate and chondroitin sulfate biosynthesis in microglias after brain injury

The fundamental difference relative to apoptosis is the rapid loss of cellular membrane potentials due to energy depletion and ion pump/channel failures, leading to swelling, rupture, and cytolysis

After being abundantly absorbed by the cells it inhibits tyrosinase production which reduces melanin synthesis

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Tanito M, Nakamura H, Kwon YW, Teratani A, Masutani H, Shioji K, Kishimoto C, Ohira A, Horie R, Yodoi J