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doi: 10.1006/bbrc.1996.1550

A monothiol mechanism was also reported for the in vitro reduction of mammalian RNR 46 and can be also employed, although with a decreased activity, by a Grx-RNR fusion protein from Facklamia ignava 47

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While the hallmark of this disease is ataxia, patients are also prone to diabetes, scoliosis, hearing and vision loss, and cardiomyopathy 166,167,168,169

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