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Intervention study While the studies cited above are largely consistent with the existence of a high-folatelow-vitamin B-12 interaction affecting both tHcy and MMA metabolism, data are limited on the effect of high-dose folic acid supplements on these 2 biomarkers in vitamin B-12deficient individuals

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Photomicrographs were taken using a transmitted light microscope (Olympus Vanox, Olympus, Tokyo, Japan)

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It is characterized by bulbous body which is hermetically sealed

Supplementation with B-vitamins, including folate, vitamin B 6 and B 12 have been shown in numerous studies to help lower homocysteine levels