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Altering microglial responses via metabolic reprogramming holds promise for treating AD and other NDDs

Severe allergic reactions: Recognize symptoms (rash, difficulty breathing, swelling) Discontinue the peptide immediately Provide emergency medical treatment (epinephrine if anaphylaxis) Transport to an emergency facility if needed Document and report Exclude from further research Hypoglycemia: Recognize symptoms (shakiness, sweating, confusion) Administer fast-acting carbohydrates immediately Monitor blood glucose Seek medical evaluation if severe Adjust the protocol to prevent recurrence Other serious adverse events: Clear protocols for recognition and management Access to medical care Documentation and reporting requirements Communication with research oversight bodies Review of protocols if serious events occur Safety Documentation Proper documentation of safety is essential

J Am Chem Soc 2023, 145 (5), 27542758

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In: Molecular Plant Abiotic Stress: Biology and Biotechnology

Furthermore, studies done with acetylcholinesterase inhibitors, which are common AD treatments, showed the reversibility of reactive astrocytes to a healthy state after treatment 151