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The SURPASS clinical trial program, which evaluated tirzepatide in over 10,000 patients with type 2 diabetes, did not identify palpitations as a significant safety signal

Cuadrado et al., 2020

Maintaining improvements long-term requires either continued use or transition to lifestyle interventions that sustain AMPK activation (resistance training, caloric cycling)

Acknowledgements Not applicable Funding No specific funding was received for this study

The ability of lung cells to maintain appropriate antioxidant responses is crucial for protecting against smoking-induced oxidative stress

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