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However, if youre sensitive to caffeine, avoid taking it with highly caffeinated beverages before bed

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Furthermore, acetylcarnitine has been demonstrated to facilitate the release of neurotransmitters (e.g., norepinephrine, serotonin, dopamine, and gamma-aminobutyric acid)

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Also, oxaliplatin-induced mechanical hyperalgesia is reduced in germ-free mice and in mice pretreated with antibiotics, which further suggests that the gut microbiota promotes the development of oxaliplatin-induced mechanical hypersensitivity and neuroinflammation