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It acts at the epicenter of discoloration formation, helping to inhibit excessive melanin production and reduce the appearance of hyperpigmentation and dark spots

Figure 1 2 Rheumatic diseases and the gut microbiota Rheumatic conditions cover a wide range of conditions that affect the joints, muscles, connective tissues and immune system (13), such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), ankylosing spondylitis (AS), psoriatic arthritis, and FM (14)

10.1016/j.nbd.2016.02.011 36 MazaratiA.MarosoM.IoriV.VezzaniA.CarliM

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Acknowledgements Not Applicable