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The mechanisms underlying this selectivity remain to be fully elucidated but may involve localized interactions between specific proteins and GSH-degrading enzymes, resulting in enzyme-centered sub-compartmentalized GSH depletion

doi: 10.1016/j.redox.2022.102477

To demonstrate that suppression of p70S6K protein and pNPM1 by RSL3 is GPX4 inhibition-specific in PTC cells, we treated K1 cells with RSL3 (3 M) in the presence of ferrostatin-1 (5 M), an effective inhibitor of ferroptosis and analyzed by Western blotting

While sterile water must typically be used immediately after opening, bacteriostatic water can be used multiple times while maintaining sterility when stored correctly

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& Mackos, A