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Cancer-related fatigue A systematic review and meta-analysis by Marx (2017) evaluating the efficacy of L-carnitine supplementation for the treatment of cancer-related fatigue included three RCTs (Hershman 2013, Cruciani 2012/2018, Kraft 2012)

doi: 10.1074/jbc.M414548200

The vasodilatory effects are certainly directly related to NO levels while the increased power output may be related to increased cellular supply of the propionate unit which when converted to succinate provides an anaplerotic energy substrate