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Studies have found that Htr4 gene expression is suppressed in the hippocampus of AD patients, and activating 5-HT4 receptors can improve cognitive function [60, 61]
Kimborough CK, Griffiths CE, Finkel LJ, Hamilton TA, Bulengo SM, Ellis CN

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The EV transfected cells did not have any effect and was similar to that of control cells
