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Electrolytes and liver tests were normal

Because MOTS-c enhanced cellular resistance against metabolic/oxidative stress 17 , we tested if MOTS-c treatment improved skeletal muscle adaptation to metabolic stress using C2C12 mouse myoblast cells

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Ethics statement All experimental procedures and animals were approved by the Fujian Agriculture and Forestry University Animal Care and Use Committee (Approval ID: PZCASFAFU24046)

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