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Second, glucose induces a structural shift in GCK into a more active conformation, making the protein more active as glucose concentrations increase (126)

Energy contribution of octanoate to intact rat brain metabolism measured by 13C nuclear magnetic resonance spectroscopy

Methods to quantify the potential of human fecal samples to produce TMA have been developed, providing an effective tool for establishing specific therapeutic strategies to inhibit TMA production (79, 80)

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Interestingly, the CrAT activity is reduced during obesity and aging, leading to impaired glycemic control 65
