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Most headaches are related to how the Botox is injected or the temporary irritation from the procedure, and not from the Botox itself

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While roGFP2 WT was completely oxidized at even very low PfGrx C32S/C88S (SSG) concentrations, 1 M PfGrx C32S/C88S (SSG) glutathionylated approximately 50% of 1 M roGFP2 C151S (SH) suggesting that the redox couples roGFP2 C151S (SSG)/roGFP2 C151S (SH) and PfGrx C32S/C88S (SSG)/PfGrx C32S/C88S (SH) have very similar redox potentials
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[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Li Y., Spence J.D., Wang X., Huo Y., Xu X., Qin X

4 : 693696 Takagi Y, Mitsui A, Nishiyama A, Nozaki K, Sono H, Gon Y, Hashimoto N and Yodoi J (1999) Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage