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The activation of specific signaling pathways, including Wnt, PI3K/AKT, Hedgehog, and NOTCH, contributes to the maintenance of quiescence in LSCs

reports in the literature estimate that up to 86% of COPD patients are treated with ICS, regardless of COPD severity and exacerbation risk [91]

Ascorbate as a co-factor for Fe- and 2-oxoglutarate dependent dioxygenases: physiological activity in tumor growth and progression