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During protein folding stress, the sirtuin SIRT7 also plays an important role by contributing to repressing nuclear respiratory factor 1 (NRF1) activity, a major transcriptional regulator of mitochondrial genes

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Statistical Analysis Demographic and clinical characteristics were analyzed using independent samples t-tests (continuous variables) and chi-square tests (categorical variables)

Thermal sweating was notably associated with clusters of activation in the posterior and pregenual cingulate cortex, and only thermal sweating was associated with activation in the anterior hypothalamus/POA region