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doi: 10.3892/ijo.2019.4942 241 Garca-GmezPGolnIDadrasMSMezheyeuskiABellomoCTzavlakiKet al
Energy failure in astrocytes increases the vulnerability of neurons to spreading depression
The disruption of this network produces organelle-specific imbalances that propagate into cellular dysfunction and contribute to a wide spectrum of human diseases, including neurodegeneration, cancer, metabolic disease and developmental disorders
& Frangogiannis, N
GNMT deficiency is inherited as an autosomal recessive disorder associated with hypermethioninemia, elevated serum SAM levels, and normal levels of sarcosine
