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Stem cell therapy simultaneously targets inflammatory responses and fibrotic processes through multimodal therapeutic mechanisms such as paracrine effects and immunomodulation, which has shifted the treatment paradigm from single-target interventions to multi-mechanism synergistic approaches
[DOI] [PubMed] [Google Scholar] Hinchman C.A., Rebbeor J.F., Ballatori N

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
Qadeer A, Anis M, Warner GR et al (2024) Global environmental and toxicological data of emerging plasticizers: current knowledge, regrettable substitution dilemma, green solution and future perspectives

The change of brain microenvironment caused by acute cerebral I/R is the main obstacle to nerve function recovery, and a significant reason of stroke recurrence after thrombolytic therapy
