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Description
This apparent contradiction can be explained by considering alternate sources of pyruvic acid

This review emphasizes that amino acid metabolism is not an isolated regulatory module, but rather part of an interconnected network that, together with glycolysis, the pentose phosphate pathway, tricarboxylic acid cycle anaplerosis, one-carbon metabolism, and lipid metabolism, determines macrophage fate

Multiplatform analytical methodology for metabolic fingerprinting of lung tissue

Transmit sense

This disparity is hypothesized to arise from differences in estrogen-mediated neuroprotection, lifestyle factors, and occupational exposure to neurotoxins (Ben-Shlomo et al., 2024) (Figure 2)
doi: 10.1016/j.freeradbiomed.2004.05.034
