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NMDAR-dependent LTP is therefore an associative form of plasticity and fulfills the criteria for correlated activity as the origin of the strengthening of the connection between two neurons proposed by Donald Hebb more than 60 years ago (Hebb 1949)

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Materials and methods Animals and experimental design C57BL/6J mice with the transgenic 5xFAD genotype (JAX, Bar Harbor, Maine) of both sexes were used

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Mutations in the concerned viral proteins may render the immune system to preferentially utilize the immunological memory from a previous infection during the encounter with a slightly different strain of the virus and may boost non-neutralizing antibodies, these non-neutralizing antibodies may reduce the efficacy of vaccines and for this reason, the vaccine for Influenza requires to be developed every year 87,88,89