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GSTK1 may also be responsible for the detoxification of lipid peroxides created in the peroxisome based on the peroxidase activity towards three substrates: tert-butyl hydroperoxide, cumene hydroperoxide, and 15-S-hydroperoxy-5,8,11,13-eicosatetraenoic acid

doi: 10.3390/biomedicines11112994 158 JiaX.ZhangS.TanS.DuB.HeM.QinH.et al

Nerve impulses trigger the release of glutamate from the presynaptic cell

and (3) molecular and cellular dysregulations involving syn aggregation, mitochondrial impairment, oxidative stress, neuroinflammation, and iron dyshomeostasis