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( FIGURE 1 2.1 NO synthase isoforms and their roles in CRC Each isoform plays a unique role in the pathophysiology of CRC, as mentioned in Table 1

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In normoxia, pyruvate enters cellular mitochondria through the mitochondrial pyruvate carrier (MPC) to begin the second reaction phase of the aerobic oxidation pathway

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The dispersed distribution of the scaffold-type proteins, particularly those characterized as the carrier or transfer proteins, is important for the determination of the mechanistic specificity of the FeS cluster assembly systems