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Clinical course of COVID-19 patients treated with ECMO: a multicenter study in Daegu, South Korea

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One heavy session can delay soft-tissue healing by 5-7 days based on inflammatory marker recovery times (Koyuncu et al., 2025)

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Homocysteine also stimulates the growth of smooth muscle cells, causing deposition of extracellular matrix and collagen

Myofibroblasts can be originated from different sources, including tissue resident fibroblasts, epithelial and endothelial cells undergoing epithelial/endothelial-to-mesenchymal transition (EMT/EndMT), as well as from circulating fibroblast-like cells named fibrocytes, originated from bone-marrow stem cells [12]