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We were unable to robustly increase bulk acetyl-CoA or consistently increase histone acetylation on addition of acetate in shTMLHE cells (Extended Data Fig

As a result of more successful treatment of BC, there is a growing number of BC-survivors facing unique long-term physical, psychological, and psychosocial changes, which can significantly impact their quality of life [4]

231 Consequently, a growing body of evidence suggests that lactate-derived lactylation plays a critical role in various biological processes of neurological disorders such as Alzheimers disease (AD), cerebrovascular diseases, brain tumors, traumatic injuries, and psychiatric disorders 232,233,234 (Figs

Natural polyphenols in drug delivery systems: current status and future challenges

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