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It is well known that in areas with severe and chronic iodine insufficiency, hypothyroidism can occur in both mothers and fetuses from the early stages of gestation, leading to irreversible brain damage, mental retardation, and neurological abnormalities [11,12]

In the CSp-OxD hydrogel, the peak observed at 1645 cm 1 signifies the presence of a carbon-nitrogen double bond, corroborating the formation of a Schiff base, while the peak at 1375 cm 1 signifies a boron-oxygen single bond, confirming the formation of a borate ester bond (Fig

Residual moisture content for all the formulations is provided in the supplementary data section

Obeticholic acid, a semisynthetic bile acid analog, is an agonist of the farnesoid X receptor, which has anti-inflammatory and antioxidant activities (155)

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Increase dietary consumption of key vitamins for skin health