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So far, our discussions of these reactions have been largely qualitative

Immunogenicity concerns: In particularly high or concentrated doses above whats typically used, TA-1 may pose a risk for immunogenicity

Similarly, 60% of patients had immune-related major pathologic response (irMPR) with two complete pathologic responses, and 40% had partial response (PR) with the percent residual viable tumor ranging from 25% to 65%

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This matters even more in cash-pay weight loss, where many virtual clinics operate through MSO structures specifically to stay on the right side of CPM rules and, where relevant, to support payer reimbursement

Initial effectiveness data for APHD-012 is expected by the end of 2024 following the completion of phase 2 trials