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Oncogenic roles of the PI3K/AKT/mTOR axis
An increasing amount of evidence much of it clinical suggests that migraine is a response to cerebral energy deficiency or oxidative stress levels that exceed antioxidant capacity and that the attack itself helps to restore brain energy homeostasis and reduces harmful oxidative stress levels

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126 However, fecal microbiota transplantation from lean vegans to patients with metabolic syndrome did not yield a significant change in gut TMAO production and failed to improve the signs of endothelial dysfunction
Supplementary Information Additional file 1: Fig

PMID 17331998