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44 were supplemented with L-carnitine (15 mg/kg iv after each hemodialysis for 6 months), while 39 took placebo

Albeit larger studies are necessary to validate and strengthen the biomarker potential and the therapeutic benefits of targeting these pathways before translation into clinical practice is attainable
These findings guide clinical practice while highlighting research priorities to fully establish NACs therapeutic potential in respiratory medicine

Beyond ECM degradation, MMPs also play critical roles in regulating inflammation and cellular behaviour by modulating growth factors, cytokines, chemokines, and cell surface receptors, thereby orchestrating a complex network of signaling events that ultimately drive IPF progression (Karsdal et al., 2016)

[DOI] [PubMed] [Google Scholar] 702.Kovaleva, V
