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In line, low serum-magnesium levels have been associated with an increased cardiovascular risk and all-cause mortality in the general population (13)

& Sahoo, M

they simply indicate that further research is warranted

Revised April 2021

Further research is also needed to determine the influence of chronic circadian misalignment in circadian rhythm sleep-wake disorders as our model of chronic circadian misalignment perhaps bests mimics such conditions (e.g., non-24 hour)

There are many more clinical studies that are currently underway to generate the necessary evidence of its efficacy to inform future patient care and clinical action (Table 2)