dihexa peptide neurotrophic cognitive AngIV-Analog Rescues Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway Dihexa - PRAMAH / THE
Description
doi: 10.1161/01.CIR.0000114133.99074.96

For ongoing care: 1 mL (1000 mcg) given as an intramuscular shot once a month

Referenced Citations Teichman, S
The downstream effects most consistently described in the literature: induction of collagen I and III, elastin, and decorin synthesis (Maquart et al., FEBS Letters , 1988), upregulation of VEGF and basic FGF transcripts, induction of antioxidant defense genes including SOD2 and metallothionein isoforms, and modulation of the MMP-2 and TIMP-1/2 balance toward non-fibrotic remodeling

Meta-analysis covering 36 distinct research papers from 1993 to present, evaluating structural and biomechanical tissue parameters

Elmo Bud Zumwalt
