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Fully achieved reduction of severe lesions in the brain, heart, lungs, liver, kidneys, and gastrointestinal tract reduced thrombosis in both veins and arteries, peripherally and centrally, and fully abrogated intracranial (superior sagittal sinus), portal, and caval hypertension and aortal hypotension may be regarded as a proof of concept
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Leaky gut

Furthermore, previous evidence suggests that formation of unfolded proteins in astrocytes could induce the inflammatory responses previously mentioned [117]

PLoS ONE 15, e0234255