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Glucose can covalently react with lysine, arginine, and the N-terminal residues on proteins to form glycation products, which can further react to produce advanced glycation end products (AGEs) [102]

10 , e991570 (2015)

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Loss of up to 25%80% of the mtDNA genome compromises the assembly and function of, ETC., complexes, attenuates proton pumping, and leads to dissipation of mitochondrial membrane potential (m) (Robichaux et al., 2023)