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Environmental neurotoxic chemicals-induced ubiquitin proteasome system dysfunction in the pathogenesis and progression of Parkinson's disease

There remains potential in the role of modifier genes that have not been identified yet, looking at direct D4Z4 binding proteins [140] or gender specific effects of DUX4 signalling [133]

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To minimize toxicity, acryloyl-CoA is rapidly reduced back to propionyl-CoA by acryloyl-CoA reductase

This switch reduces reactive oxygen species steady-state levels within granulosa cells and Sertoli cells, imposing less oxidative strain on oocytes and sperm

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