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Peter Marks, director of the FDA's Center for Biologics Evaluation and Research, said in a statement

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Moreover, in an in vitro model of blast-induced auditory hair cell damage, 3-AB inhibition of PARP1 reduced oxidative stress markers, upregulated antioxidant defenses, and helped maintain cell viability by preserving ATP pools 175

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Root Cause: Many payers require that the diagnosis tied to the injection align with approved indications for the drug
