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ROS can trigger OS, which negatively impacts sperm motility, morphology, and DNA integrity, resulting in reduced fertility [17]

[DOI] [PubMed] [Google Scholar] 119.Provenzale D., Reinhold R.B., Golner B., Irwin V., Dallal G.E., Papathanasopoulos N., Sahyoun N., Samloff I.M., Russell R.M

This study also revealed a significant correlation between XBP1s binding and HIF1 motifs, indicating that XBP1s may play a role in hypoxia adaptation and stem cell maintenance

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H3K4 tri-methylation (H3K4 me3 ) and H3K27 me3 marker active and repressive gene transcriptions respectively in cells