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Description
Park, Do Y

Critical prosurvival roles for C/EBP beta and insulin-like growth factor I in macrophage tumor cells

P.CherianM

The conformational flexibility of TM11 appears to be linked with substrate recognition, with R471 (responsible for carnitine coordination) located near the midpoint of this helix, between the two segments that bend during the transition between inward-facing and occluded conformations

Miura K, Yang L, van Rooijen N, Brenner DA, Ohnishi H, Seki E (2013) Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice

Evidence: A 2024 review noted it helps strengthen the heart muscle and improve its pumping efficiency
