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IL-31 is mainly secreted by Th2 cells, and dermal CD11c + myeloid dendritic cells are an important source of IL-31 in PN (33, 34)
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For example, in the strategy of targeting immune organ rejuvenation, a phase II clinical trial demonstrated the potential of miR-205 mimics to restore thymopoiesis in settings of diminished or impaired T cell output
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Hence, understanding the association between climate variables and malaria incidence is essential for effective control measures, especially as the country is on a mission to eliminate malaria by 2030 [2]
