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When beta-glucuronidase producing bacteria are allowed to overgrow it leads to elevated estrogen levels, contributing to estrogen dominance in both men and women

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A separate group of age-matched young controls (3 months old) was generated by purchasing 10-week-old mice and acclimating them for 2 weeks prior to sacrifice

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this suggests that adenosine may act as a homeostatic regulator of sleep, with higher levels promoting the need for rest (Huang et al., 2014)
