l-carnitine transport fatty acids into mitochondria Activation and Transportation of to the via the Carnitine Shuttle with Animation Acyl Carnitine Translocase: MCAT Guide

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The studies above focused on skeletal muscle, but this dysregulation in carnitine metabolism may be found in other tissues and cause other ZDV-induced ADRs such as hepatic lipid accumulation (hepatic steatosis)

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Ceravolo SA, Hammond BR, Oliver W, Clementz B, Miller LS, Renzi-Hammond LM

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VLCAD deficiency is most frequently diagnosed of all lcFAODs worldwide with a prevalence reported between 1:31.500 to 1:94.569 [55, 120]