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Structures such as lipopolysaccharides (LPS), peptidoglycans, porin complexes, lipoteichoic acid, lipoarabinomannans, bacterial DNA, mycoplasma lipoproteins, and staphylococcal and streptococcal superantigens constitute a major group of the pyrogens of gram-negative, gram-positive, and mycobacterial origin [8,9,10]