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Cellular iron uptake, trafficking and metabolism: key molecules and mechanisms and their roles in disease

BreuerTBleilevensCRossaintRMarxGGehrenkemperJDierksenHet al

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The results showed that sustained exposure to Ni NPs led to a significant inflammatory response in the liver, upregulation of ER stress sensors such as inositol-requiring enzyme 1 (IRE1), pancreatic ER kinase (PERK), and ATF6, and activation of apoptosis in liver cells