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The progressive neuronal loss, limited treatment efficacy, and enormous social and economic burden underscore the critical importance of early, targeted, and multi-mechanistic neuroprotective approaches

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Universit Bourgogne Franche-Comt

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This suggests that sustained astrocytic glycolysis occurs in order to maintain the extracellular lactate pool to meet the energy requirements of neurons

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0.210.33 for UC) increasing steadily into the 2010s (CR-I: 2.203.20 for CD

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However, the lack of extensive clinical trials specifically targeting its use in pregnant women raises questions about its safety and efficacy

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