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J.et al (2024)

Consider Cost and Practical Availability In settings where both options are clinically appropriate, practical factors may also influence selection

Light exposure : UV light damages peptide molecules

How is our nutrition

So there is plenty of evidence showing that Metformin and Vitamin B12 deficiency is a problem, especially with long term use of Metformin and this is a drug that is usually taken forever once it is prescribed Metformin And Vitamin B12 Deficiency The Solution The first thing to do is to get your vitamin B12 levels tested so that you have a baseline reading, dont follow the reference range but make sure your levels are over 400 as a minimum

Because B12 is water soluble, the body doesnt store large amounts of it long-term the way it stores fat-soluble vitamins, which is one reason ongoing dietary intake or supplementation matters for some people more than others