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Peptides: Tesamorelin, AOD9604, Tirzepatide (GLP-1 agonist) Tesamorelin is FDA-approved to reduce visceral adipose tissue (VAT) in HIV-associated lipodystrophy, but its fat-burning effects also appear in non-HIV populations Source: Falutz et al., NEJM , 2010

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Here we can envisage a scenario where these elements are diverted from their basic functions to form a unified antimicrobial response resulting in loss of function and a build-up of metal-laden aggregated microbes