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Supplementary material The Supplementary Material for this article can be found online at: FIGURE S1 | Emergent self-organized map (ESOM) of Geitlerinema sp
Kefir is produced through a fermentation process, which undergoes biochemical changes induced by a community of desirable microorganisms at room temperature for approximately one to three days (Bensmira et al., 2019

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3 Geographic variations in antileishmanial drug resistance Treatment options for leishmaniasis vary significantly by region due to differences in dominant Leishmania species and emerging drug resistance patterns ( Leishmania donovani shows high resistance to sodium stibogluconate (SSG) and declining susceptibility to miltefosine, necessitating alternatives like liposomal amphotericin B (L-AmB) and combination therapies
