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Vitamin B12 may be more effective than nortriptyline in improving painful diabetic neuropathy

However, when the limit for storage of TAGs is reached or adipocyte lipolysis is dysregulated, FAs can accumulate in ectopic tissues such as skeletal muscle and the liver leading to insulin insensitivity and T2D (11)

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When levels drop, replenishing B12 directly can help support both physical and mental well-being

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Each component has attracted attention in experimental models related to cellular signaling, tissue remodeling, and regenerative biology