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Although vitamin B 12 deficiency is known to damage the myelin sheath covering cranial, spinal, and peripheral nerves, the biochemical processes leading to neurologic damage in vitamin B 12 deficiency are not yet fully understood (22)

Effects of short-and long-duration hypothyroidism on hypothalamicpituitaryadrenal axis function in rats: in vitro and in situ studies

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They measured the full B12 body count of four people and found it to be 780 to 1,350 g of B12 with a daily loss of 0.12% for a maximum loss of 1.6 g per day or 11.2 g per week